There are many factors to consider when choosing an AWS region: latency to end-users, cost, data residency laws, inter-region latency, etc. Which makes it hard to unequivocally say which AWS region best for each unique scenario.
To give you a head start, here is a list of major countries/cities in alphabetical order, with an AWS region(s) that’s optimal, based on cost and latency.
The data for these regions is taken from another article: Which AWS Region Is Cheapest? A Costing Report, and locations have been assessed using methods described in: How To Find Which AWS Region Is Closest To You?.